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CCCB
CELL CYCLE & CANCER BIOMARKERS LAB
01/2022
GONZÁLEZ-MARTÍNEZ J,. CWETSCH A. W, GILABERT-JUAN J, GÓMEZ J, GARAULET G, SCHNEIDER P, DE CÁRCER G, MULERO F, CALEIRAS E, MEGÍAS D, PORLAN E, MALUMBRES M.
GENETIC INTERACTION BETWEEN PLK1 AND DOWNSTREAM MCPH PROTEINS IN THE CONTROL OF CENTROSOME ASYMMETRY AND CELL FATE DURING NEURAL PROGENITOR DIVISION
CELL DEATH & DIFFERENTIATION 2022.
DOI.ORG/10.1038/S41418-022-00937-W
10/2021
SOLANES-CASADO S, CEBRIÁN A, RODRÍGUEZ-REMÍREZ M, MAHÍLLO I, GARCÍA-GARCÍA L, RÍO-VILARIÑO A, BAÑOS N, DE CÁRCER G, MONFORT-VENGUT A, CASTELLANO V, FERNÁNDEZ-ACEÑERO MJ, GARCÍA-FONCILLAS J, DEL PUERTO-NEVADO L.
OVERCOMING PLK1 INHIBITOR RESISTANCE BY TARGETING MEVALONATE PATHWAY TO IMPAIR AXL-TWIST AXIS IN COLORECTAL CANCER.
BIOMED PHARMACOTHER. 2021 DEC;144:112347.
DOI: 10.1016/J.BIOPHA.2021.112347
08/2020
SANZ-GÓMEZ N, DE PEDRO I, ORTIGOSA B, SANTAMARÍA D, MALUMBRES M, DE CÁRCER G, GANDARILLAS A.
SQUAMOUS DIFFERENTIATION REQUIRES G2/MITOSIS SLIPPAGE TO AVOID APOPTOSIS
CELL DEATH DIFFER. 2020 AUG;27(8):2451-2467.
DOI: 10.1038/S41418-020-0515-2.
11/03/2019
DE CÁRCER G.
THE MITOTIC CANCER TARGET POLO-LIKE KINASE 1: ONCOGENE OR TUMOR SUPPRESSOR?
GENES (BASEL). 2019 MAR 11;10(3). PII: E208.
DOI: 10.3390/GENES10030208.
01/08/2018
DE CÁRCER G*, et al.; MALUMBRES M*, SOTILLO R*.
PLK1 OVEREXPRESSION INDUCES CHROMOSOMAL INSTABILITY AND SUPPRESSES TUMOR DEVELOPMENT.
NAT COMMUN. 2018 AUG 1;9(1):3012.
DOI: 10.1038/S41467-018-05429-5.
06/2018
DE CÁRCER G*, HUERTAS P*, LOPEZ-CONTRERAS AJ*.
CHROMOSOME INSTABILITY: FROM MOLECULAR MECHANISMS TO DISEASE
DNA REPAIR. 2018 JUNE; 66-67:72-75.
DOI: /10.1016/j.dnarep.2018.04.006
08/2017
DE CÁRCER G*, et al.; REDONDO JM*, MALUMBRES M.*
PLK1 REGULATES CONTRACTION OF POSTMITOTIC SMOOTH MUSCLE CELLS AND IS REQUIRED FOR VASCULAR HOMEOSTASIS.
NATURE MEDICINE. 2017; 23(8):964-974.
DOI: 10.1038/NM.4364
07/2016
WACHOWICZ P, FERNÁNDEZ-MIRANDA G, MARUGÁN C, ESCOBAR B, DE CÁRCER G.*
GENETIC DEPLETION OF POLO-LIKE KINASE 1 LEADS TO EMBRYONIC LETHALITY DUE TO MITOTIC ABERRANCIES.
BIOESSAYS. 2016; 38 SUPPL 1:S96-S106.
DOI: 10.1002/BIES.201670908.
10/2015
TRAKALA M, PARTIDA D, SALAZAR-ROA M, MAROTO M, WACHOWICZ P, DE CÁRCER G, MALUMBRES M.
ACTIVATION OF THE ENDOMITOTIC SPINDLE ASSEMBLY CHECKPOINT AND THROMBOCYTOPENIA IN PLK1-DEFICIENT MICE.
BLOOD. 2015 OCT 1;126(14):1707-14.
DOI: 10.1182/BLOOD-2015-03-634402.
06/2014
DE CÁRCER G, MALUMBRES M.
A CENTROSOMAL ROUTE FOR CANCER GENOME INSTABILITY.
NAT CELL BIOL. 2014 JUN;16(6):504-6.
DOI: 10.1038/NCB2978.
07/2011
DE CÁRCER G, MANNING G, MALUMBRES M.
FROM PLK1 TO PLK5: FUNCTIONAL EVOLUTION OF POLO-LIKE KINASES.
CELL CYCLE. 2011 JUL 15;10(14):2255-62.
DOI: 10.4161/CC.10.14.16494
05/2007
PÉREZ DE CASTRO I, DE CÁRCER G, MALUMBRES M.
A CENSUS OF MITOTIC CANCER GENES: NEW INSIGHTS INTO TUMOR CELL BIOLOGY AND CANCER THERAPY.
CARCINOGENESIS. 2007 MAY;28(5):899-912.
DOI: 10.1093/CARCIN/BGM019
2007
DE CÁRCER G, PÉREZ DE CASTRO I, MALUMBRES M.
TARGETING CELL CYCLE KINASES FOR CANCER THERAPY.
CURR MED CHEM. 2007;14(9):969-85.
DOI : 10.2174/092986707780362925
08/2004
DE CÁRCER G.
HEAT SHOCK PROTEIN 90 REGULATES THE METAPHASE-ANAPHASE TRANSITION IN A POLO-LIKE KINASE-DEPENDENT MANNER.
CANCER RES. 2004 AUG 1;64(15):5106-12.
DOI: 10.1158/0008-5472.CAN-03-2214
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